Created by Vinyl Revival, Plan B Agency and Factory/Hacienda designer, Trevor Johnson, the t-shirt and hoodie range is available in both adult and children's sizes.
All proceeds raised from the range will go to the Manchester University NHS Foundation Trust and the United We Stream relief fund.
Sacha Lord, Night Time Economy Adviser and founder of UnitedWeStream GM, said: “As with everything, all the best things come out of Greater Manchester, and as a Mancunian I couldn’t be more proud that the NHS came out of our city region.
"My role as Night Time Economy Adviser not only covers the hospitality and leisure industries, but everyone who grafts through the night, including the emergency services and NHS hospital workers who are continuing to work tirelessly throughout the crisis."
"For me, they are the most important people in the country at the moment and that should never be forgotten when we are through this crisis. I hope people wear this range with pride.”
Mayor of Greater Manchester, Andy Burnham said: “It is fantastic that these legendary Manchester designers have turned their talents to supporting our local NHS at this time. The maNcHeSter image will become another iconic Manchester brand and I think it will be proudly worn on our city’s streets, in our venues and hospitals for many years to come."
“Our creative community has supported us and entertained us through our United We Stream GM service and I’m so glad that the profits from this T-shirt will also help keep them going in the difficult months ahead. I will be wearing mine with complete pride.”